Early-onset Alzheimer’s: recognizing the signs for early intervention

Often mistaken for stress or exhaustion, early-onset Alzheimer’s disrupts the lives of at least 28,000 Canadians, accounting for between 2% and 8% of all neurocognitive disorder cases in the country.

We’ll help you recognize the signs of early-onset Alzheimer’s, understand its progression, and learn to live better with this form of the disease.

Early-onset Alzheimer’s: recognize the signs for early intervention

What is early-onset Alzheimer’s?

Early-onset Alzheimer’s, also known as young-onset Alzheimer’s, is a form of Alzheimer’s disease that occurs in adults under the age of 65. This means it generally affects people with busy professional lives and many family responsibilities, both of which are severely impacted by the disease.

Fortunately, knowledge and prompt diagnosis can pave the way to the right resources and a better quality of life.

When does early-onset Alzheimer’s develop?

Although it is possible for people as young as 18 to develop early-onset Alzheimer’s, it usually develops between the ages of 50 and 64. Onset before 40 is very rare. These cases are often linked to specific hereditary genetic mutations.

How to detect or diagnose early-onset Alzheimer’s

The signs of early-onset Alzheimer’s are similar to those of regular (late-onset) Alzheimer’s, but are often mistakenly attributed to stress, fatigue, or overwork, delaying diagnosis and treatment.

This form of Alzheimer’s is often detected later because its symptoms can be explained by other causes in younger people. As such, it’s important to know the signs to ensure that the disease can be diagnosed and managed as soon as possible.

Some signs to watch for

  • Short-term memory loss: Forgetting recent events or important appointments, asking the same questions over and over again, or regularly losing personal belongings become frequent occurrences that aren’t explained by everyday distractions.
  • Difficulty accomplishing familiar tasks: Preparing meals, managing money, or using everyday appliances may become more difficult, even if these tasks have been mastered for years.
  • Mood and personality changes: Unusual mood swings, anxiety, apathy, or inappropriate behaviour start to appear. The person may seem different from the one you knew.
  • Disorientation (time or space): Getting lost in familiar surroundings, mixing up dates, or no longer recognizing the seasons are all warning signs.
  • Language and communication issues: Searching for words, using inappropriate vocabulary, or struggling to follow a conversation become daily challenges that gradually lead to isolation.

How does the disease progress?

Early-onset Alzheimer’s generally progresses through three distinct stages, each with its own challenges.

  1. Early-stage (mild): The person is still independent, but starts to struggle with complex tasks. They are still able to work in an environment adapted to their situation.
  2. Middle-stage (moderate): The person needs help with many daily activities. They need supervision and usually are unable to work at this point.
  3. Late-stage (severe): The person requires full assistance in all aspects of daily life to ensure their safety and care.

Early-onset Alzheimer’s often progresses more quickly than late-onset Alzheimer’s, in part because people are diagnosed later.

What causes early-onset Alzheimer’s?

Genetics play a more important role in early-onset Alzheimer’s than in its other form. Certain inherited genetic mutations can considerably increase the risk of developing the disease before the age of 65.

Other factors can also contribute to the development of early-onset Alzheimer’s disease:

  • Family history of Alzheimer’s or other neurocognitive disorders
  • Certain chronic diseases, including diabetes and high blood pressure
  • Repeat traumatic brain injuries
  • Environmental factors

Smoking, a sedentary lifestyle, an unbalanced diet, a chronic lack of sleep, and social isolation can also increase the risk of developing early-onset Alzheimer’s.

Why is early diagnosis important?

Getting a diagnosis quickly is the key to ensuring the best possible treatment for early-onset Alzheimer’s. A doctor will help rule out other possible causes for the symptoms, such as depression, vitamin deficiencies, or thyroid problems.

Usually, confirming a diagnosis requires the following tests:

  • Cognitive tests to assess memory and other functions
  • Brain imaging (MRI or CT scan)
  • Blood tests to rule out other causes
  • An in-depth neuropsychological assessment.

Early diagnosis makes it easier to plan for the future, while the person with Alzheimer’s is still able to participate in important decisions (financial arrangements, advance medical directives, family support plans, etc.). This gives them some control over their own life.

Treatment options

Although there is no cure for early-onset Alzheimer’s, there are several ways to slow progression and improve quality of life.

Drug treatment

Certain medications can temporarily stabilize or slow cognitive decline in Alzheimer’s patients. These treatments can’t reverse existing damage in the brain, but they can offer much-needed respite and help patients maintain function for longer.

Your pharmacist can recommend medications, explain how they work, and help you manage possible side effects.

Other treatments

Complementary therapies play just as important a role as drugs in the management of early-onset Alzheimer’s. Here are a few examples:

  • Cognitive stimulation through activities adapted to the stage of the disease
  • Occupational therapy to maintain autonomy in daily activities
  • Regular physical activity adapted to the person’s abilities
  • Psychological support for the individual affected and their families
  • Specialized day programs offering stimulation and socialization
  • Music and art therapy, which can improve mood and reduce anxiety

When used in combination, these therapies help maintain abilities for as long as possible and improve the overall well-being of the person with Alzheimer’s.

Associations and support resources

No one should face Alzheimer’s on their own. A strong support network is essential. Here are some of the resources available to support and equip people with Alzheimer’s and their families.

  • The Alzheimer Society offers programs tailored to people living with Alzheimer’s and their families, including specific support groups.
  • The Info-Santé line (811) is available day and night to answer your questions, advise you, and direct you to the appropriate resources.
  • Respite programs allow caregivers to take a well-deserved break.
  • L’Appui proches aidants offers services tailored to the realities of families affected by Alzheimer’s.

You can count on your pharmacist for support

Your Brunet pharmacist provides expert, caring support to people with Alzheimer’s and their loved ones. Through their accessible and confidential service, your pharmacist can help you understand your treatments, prevent drug interactions, and support you in the daily management of Alzheimer’s symptoms.

You are not alone

With early diagnosis, the right treatment approach, and a strong support network, people with Alzheimer’s can maintain their quality of life and continue to enjoy memorable moments with their loved ones.

Are you worried about yourself or a loved one? Don’t hesitate to ask for help: it’s the first step to getting the support you need!

Last updated on July 10, 2025

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